Staphylococcal scalded skin syndrome
☆ د آلمان څخه د 2022 سټیفټنګ وارینسټ پایلو کې ، د ماډلډرم سره د مصرف کونکي رضایت د تادیه شوي ټیلی میډیسن مشورې په پرتله یوازې یو څه ټیټ و.
یو ماشوم د Staphylococcal scalded skin syndrome سره
References
Staphylococcal Scalded Skin Syndrome هغه حالت دی چې د پوستکي د زهرجن موادو له امله چې د ځانګړي ډول سټیفیلوکوکس باکتریا لخوا تولید شوي وي. دا په شپږو کلونو کې په ماشومانو کې غیر معمولي ده. دا په لویانو کې هم پیښ کیدی شي چې د معافیت سیسټم ضعیف یا د پښتورګو جدي ستونزې ولري. اصلي ځانګړتیا د سوځیدنې وروسته د پوستکي پراخه کول دي. شدت د یو څو ټوټو څخه نیولې د پوستکي پراخه ضایع کیدو پورې اړه لري، کوم چې کولی شي د بدن د حرارت درجه کې د شدید کمښت او د وینې فشار کې بې ثباتۍ سبب شي.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
یو لس میاشتنی هلک راغی چې پزې بهیږي او ښه نه خوري. ډاکټرانو وویل چې دا د پورتنۍ تنفسي ناروغي وه. دوه ورځې وروسته، هغه بیرته راغی ځکه چې هغه ښه نه و او نوې ستونزې لکه پړسوب او د خولې شاوخوا خارښ شوی پوستکی. په راتلونکو دوو ورځو کې، هلک خراب شو. د هغه لاسونه او پښې پړسیدلې او پوټکی یې راوتلی. بیرته روغتون ته، ډاکټرانو د هغه په مخ او د هغه د پوستکي په پوښونو کې سور داغ ولید، چې د لمس کولو په وخت کې روښانه کیږي. دوی هغه د staphylococcal scalded skin syndrome (SSSS) سره تشخیص کړ او د رګ له لارې یې انټي بیوټیکونه پیل کړل.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
یوه 2 کلنه نجلۍ د هغې په ټول بدن کې د داغونو سره ښکاره شوه چې په 48 ساعتونو کې یې وده کړې وه، یوه ورځ مخکې د هغې په مخ د حشراتو د چیچلو وروسته. د معاینې په جریان کې، هغې د کوچنیو ټوټو څخه جوړه شوې پراخه داغونه درلودل چې یوځای سره یوځای شوي، او کله چې په نرمۍ سره مینځل کیږي، د هغې پوټکي د نیکولسکي نښې نښانې ښکاره کړې. داسې نښې نښانې نه وې چې د هغې په مغز باندې اغیزه وکړي. د هغې په وینه کې معایناتو د انفیکشن هیڅ نښه نده ښودلې.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
سنډروم د ایپیډرمولیتیک ایکسوټوکسین (ایکسفولیټین) A او B لخوا رامینځته کیږي چې د S. aureus لخوا خوشې کیږي. په ماشومانو کې د staphylococcal scalded skin syndrome تشخیص خورا ښه دی، د درملنې په 10 ورځو کې بشپړ حل سره، او د پام وړ داغ پرته. په هرصورت، staphylococcal scalded skin syndrome باید د زهرجن ایپیډرمل نیکرولیسس څخه په احتیاط سره توپیر ولري، کوم چې ضعیف تشخیص لري.
○ تشخیص او درملنه
د ایکزیما د زخمونو په توګه غلط تشخیص لکه د atopic dermatitis، او د سټرایډ مرهم کارول زخمونه لا پسې زیاتوي. مهرباني وکړئ ژر تر ژره د طبي پاملرنې غوښتنه وکړئ کله چې د انټي بیوټیک مرهم تطبیق کړئ.
#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)